Lifen Datalab
France-PAD network
Launched in July 2025, France-PAD federates 6 hospital centers to structure and exploit clinical data on lower limb arteriopathy, with the aim of improving patient care and the evaluation of innovative devices.
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Project background & objectives

Launched in 2025, France-PAD is a national clinical investigation network dedicated to obliterative arteriopathy of the lower limbs (AOMI), a disease that affects nearly a million people in France, with a prevalence of up to 29% in high-risk vascular patients.

Coordinated by Hôpital Paris Saint-Joseph and financed by the ANR, this network brings together 6 hospitals representing 8% of national AOMI activity. The project aims to structure and exploit clinical data to better understand the disease, improve patient management and facilitate the evaluation of innovative medical devices.

1 M
People affected in France
+6
Participating centers
94
Variables of interest

The patient's voice

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Participating centers
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Inclusion criteria & study variables

The France-PAD network targets all patients affected by obliterative arteriopathy of the lower limbs (AOMI). The database is made up of numerous variables covering the following areas:

  • Genre,
  • Date of birth,
  • vital status,
  • FAMILY NUMBER,
  • puberty etc...
  • FAMILY HISTORY OF AOH,
  • comorbidities,
  • AFFECTED FAMILY MEMBER(S) ETC...
    • DIAGNOSIS DATE,
    • DATE OF 1ST EXPERIMENT,
    • type of hereditary angioedema,
    • NATURE OF DEFICIT C1NH,
    • BIOLOGICAL CHECK-UP, ETC.
    • TREATMENT NAME,
    • DOSE,
    • FREQUENCY OF ADMINISTRATION,
    • SIDE EFFECT(S) ETC...
    • LOCATION OF THE CRISIS,
    • TRIGGERING FACTOR,
    • DURATION OF THE CRISIS,
    • TYPE OF TREATMENT,
    • treatment efficacy etc...
    • TYPE OF INTERCURRENT EVENT,
    • SHORT-TERM PROPHYLACTIC TREATMENT,
    • INTERCURRENT EVENT FOLLOWED BY A CRISIS ETC...
    • Genre,
    • Date of birth,
    • vital status,
    • DATE OF DEATH,
    • Cause of death etc...
    • SMOKING STATUS,
    • consumption of canNabis,
    • vital status
      • DIAGNOSIS DATE,
      • METASTATIC AT DIAGNOSIS,
      • TNM STATUS AT DIAGNOSIS,
      • HISTOLOGICAL SUBTYPE,
      • metastatic sites,
      • MUTATIONS etc...
      • TYPE OF TREATMENT,
      • drugs used,
      • BETTER RESPONSE TO TREATMENT,
      • PROGRESSION ETC...
      • AGE,
      • SIZE,
      • WEIGHT,
      • SMOKING (PACKAGE/YEAR),
      • Allergies etc...
      • Patient with ENT symptoms,
      • cardiovascular disease,
      • nasosinus polyposis, etc...
        • Bronchodilator treatment(s),
        • NAME of bronchodilator,
        • dose of bronchodilator,
        • bronchodilator frequency etc...
        • Assessment of the number of exacerbations,
        • number of exacerbations,
        • reason for hospitalization etc...
          • GENRE,
          • DATE OF BIRTH,
          • vital status,
          • SMOKING (PACKAGE/YEAR),
          • Allergies etc...
          • SMOKING STATUS
          • ONCOLOGICAL HISTORY ETC...
            • Evaluation of eva,
            • Evaluation of das-28,
            • Anti-ccp ac results (u/ml),
            • Biopsy results etc...
            • symptomatic treatments
            • fund processing
            • biotherapies
            • stopping treatment etc...
            • GENRE,
            • DATE OF BIRTH,
            • comorbidities,
            • Size in cm,
            • WEIGHT etc...
            • ASSESSMENT OF SYMPTOMATOLOGY,
            • VALUATION DATE,
            • claudication ETC...
              • DATE OF INTERVENTION,
              • type of anesthesia,
              • existence of a puncture,
              • LOCATION OF PUNCTURE,
              • EXISTENCE OF AN ARTHÉRIOGRAPHIC BALANCE SHEET etc...
              • POST-OPERATIVE FOLLOW-UP DATE,
              • PRESENCE OF A COMPLICATION,
              • LOCATION OF COMPLICATION,
              • DEATHS etc...
              • HOSPITALIZATION,
              • DATE OF ADMISSION TO HOSPITAL,
              • HOSPITAL DISCHARGE DATE,
              • COMPLICATIONS DURING HOSPITALIZATION etc...

              Scientific Committee

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              Key dates

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              Posters & Publications

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              Research projects

              Here you will find all the study projects using the cohort. These projects comply with the regulatory framework and have been approved in advance by the cohort's scientific committee:

              Patients

              Why take part in the project?

              Some of your medical and administrative data is collected when you are treated in a healthcare facility. This data is useful for the advancement of research.

              This research, conducted in the public interest, aims to develop knowledge in order to develop new treatments or improve the overall management of patients suffering from the same disease as you. If you agree to your data being used for this study, you will not have to make any additional visits or undergo any additional examinations.

              Only information already in your medical file will be collected. No directly identifying data (surname, first name or contact details) will be included in the cohorts.  

              If you wish to object to the processing of your data, you may exercise your rights by informing :

              If you wish to object to the processing of your data, you may exercise your rights by informing :

              • your hospital doctor treating you for angioedema or ;
              • Lifen's Data Protection Officer at the following address: dpo@lifen.fr ;
              • or by completing the opposition form.

              Would you like to find out more?
              Fill in your details, and our teams will get back to you as soon as possible.
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